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Cheryl Guttman Krader
Investigational wet AMD therapies aim for innovative targets
Many investigational drugs under development for the treatment of neovascular age-related macular degeneration (nvAMD) have advanced into the clinical trial stage, including several that are being evaluated in pivotal trials, said Peter K. Kaiser, MD.
Formula for achieving successful multifocal IOL outcomes
Achieving satisfaction for patients interested in a multifocal IOL begins with comprehensive preoperative screening and evaluation.
Non-invasive punctal plug delivery system offers a host of positive performance characteristics
A silicone punctal plug-based delivery system for ophthalmic medications (Evolute, Mati Therapeutics) provides precisely controlled medication release into the tear film and has been associated with positive results in initial clinical testing.
Exploring off-label, investigational approaches for allergic conjunctivitis
Seasonal and perennial allergic conjunctivitis are common conditions that are not always well-controlled with conventional therapy. Alternative approaches and novel investigational treatments are discussed.
Novel topical peptide for dry eye tackles underlying cause of disease
A phase I/II trial enrolling patients with Sjögrens syndrome dry eye will be investigating  a synthetic fragment of a naturally occurring tear glycoprotein. Findings from extensive laboratory and preclinical research suggest that it is a promising novel therapy.
Novel anti-VEGF-A agent shows promise for prolonged DME activity
Abicipar pegol (Allergan/Molecular Partners) met its primary and key secondary endpoints and demonstrated an acceptable overall safety profile in a phase II trial investigating use of the novel anti-VEGF-A agent for treatment of diabetic macular edema (DME).
Sustained-release corticosteroid implant improves, slows progression of diabetic retinopathy
Sustained intraocular delivery of fluocinolone acetonide (FAc) using the FAc 0.19 mg intravitreal implant (Iluvien, Alimera Sciences) improves and slows progression of diabetic retinopathy (DR), according to findings of post-hoc analyses of data from the pivotal Fluocinolone Acetonide for Diabetic Macular Edema (FAME) trials.
Pulse technology boosts all-laser PRK for one-step, no-touch ablation
Pulse technology boosts all-laser PRK for one-step, no-touch ablation
A transepithelial PRK (TransPRK) procedure (SmartSurface, Schwind eye-tech-solutions) provides the benefits of one-step, no-touch surface ablation plus rapid visual recovery, said Diego de Ortueta, MD.
Handheld polarizing filter augments corneal imaging with simple approach
Use of a handheld circular polarizing filter to intercept afferent and efferent light from a slit lamp or operating microscope highlights corneal structures that are otherwise invisible or barely seen.
Homeopathy for endometriosis pain?
Potentized estrogen was found to be effective in a recent study.

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