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New gene linked to breast cancer riskMutations in the PALB2 gene may be associated with a significant increase in the risk of breast cancer, according to a recent study in The New England Journal of Medicine. PALB2 binds to BRCA2—a gene that confers increased lifetime risk of developing breast or ovarian cancer—and likely permits its stable nuclear localization and accumulation.
Case: Molar pregnancy develops into choriocarcinomaAn ob/gyn neglects to follow a molar pregnancy to its conclusion and the patient develops choriocarcinoma. A jury found in favor of the plaintiff.
Clearing up HRT confusionThe British Menopause Society (BMS) on May 23 released updated recommendations on hormone replacement therapy (HRT), claiming that they are finally providing clarity to this murky issue. The new guidelines appear in the society’s flagship journal, Menopause International. Developed by a panel of experts, the guidelines discuss how women can optimize their menopause transition, focusing in particular on lifestyle and diet and the pros and cons of complementary therapies.
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