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    Fertile technologies

    Devices and apps for in-home use help couples take charge of their fertility.




    At first glance, Ava looks like a FitBit, Jawbone, AppleWatch, or any other wearable device. While it doesn’t tell time like the other devices, it does integrate 9 distinct parameters to help predict a woman’s fertile window. Ava measures resting heart rate, skin temperature, heart rate variability, sleep, breathing rate, movement, perfusion, bioimpedance (the resistance of body tissue to tiny electric voltages), and heat loss. These millions of data points are continuously collected while the user is sleeping and they are wirelessly synced to the user’s phone in the morning. Then, through use of a proprietary Ava app, the user is alerted to when she is in her “fertile window.”

    One of the reasons that I like the device is that the Ava algorithm is rooted in real patient data. In a small observational study (41 patients), the researchers at Ava measured the aforementioned 9 parameters in 155 menstrual cycles. The data gathered were cross-referenced with urine tests taken during the fertile phase. According to the manufacturer’s website, Ava was found to identify an average of 5.3 fertile days per cycle with an accuracy of nearly 89%.

    While I’ve yet to have a patient show me her Ava data, if a patient were to ask me if there were a near-effortless device for monitoring her cycle, Ava would definitely be at the top of my list!



    The etiology of infertility is estimated to be 40% female in origin, 40% male, and 20% unknown. However, it seems that nearly all fertility-related apps and devices are focused on the female partner. That is, until Trak. Trak is a portable centrifuge that offers men an easy and discreet way to estimate their sperm count in the privacy of their own homes. In the same way that women can monitor their ovulation through urine dipsticks, thereby avoiding blood tests in the fertility clinic, Trak lets men get a rough estimate of one of their semen parameters (concentration) without the need to schedule a semen analysis at a fertility clinic.

    Users simply produce a semen sample at home, use the included dropper to fill a disposable propeller-shaped cartridge with it, and place the cartridge in the centrifuge. The device spins the sample to help separate the sperm cells from associated cellular debris. Once the sample is fully spun, demarcations of the cartridge offer semi-quantitative guidance on the measured sperm count, such as “low” (<15 million/mL), “moderate” (<55 million/mL), or “optimal” (>55 million/mL). These parameters are based on the clinical recommendations of the World Health Organization guidelines as well as numerous clinical studies comparing couples’ time to achieving pregnancy with varying sperm counts.

    Quite often one of the final pieces of information that I will gather about a couple is the man’s semen parameters. Sometimes this is due to simple scheduling difficulties, but sometimes it is due to the patient feeling embarrassed and uncomfortable producing a specimen in the clinic. With Trak, patients can now discreetly tell whether they have sperm, and if so, how much. That data help improve the yield of the initial office visit.

    Next: Gadgets for health tracking

    These 3 apps/devices are helpful resources for our patients. Fertility tracking devices can be used to help optimize the time of intercourse, to help prevent pregnancy, or simply to help women know more about their bodies.

    I’m pleased to see that fertility-related devices are now being made for men, and I hope that companies such as Trak will start to address other semen parameters such as morphology and motility. Fertility is such an important topic, and also so sensitive, so it’s wonderful to see that at-home innovations are the leading fertility technologies of 2016.

    Brian A. Levine, MD, MS, FACOG
    Dr. Levine is Practice Director at the Colorado Center for Reproductive Medicine, New York, New York.


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