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Genetic Health Testing - OBGYN

Genetic profiles may predict future psychiatric diagnoses for patients with common deletion syndromeResults of a recent study suggest the possibility that in the future, genetic profiling may be used to identify whether children with 22q11.2 Microdeletion Syndrome (22q11.2DS; Velocardiofacial/DiGeorge syndrome) are at risk for developing autism spectrum disorder (ASD) or psychosis.
Failed cfDNA screen may signal increased risk of fetal aneuploidy
Failed cfDNA screen may signal increased risk of fetal aneuploidyWomen who fail one or two such screens need additional counseling.
Surgical options for reducing risk in BRCA mutation carriers
Surgical options for reducing risk in BRCA mutation carriersAmong BRCA mutation carriers, risk-reducing bilateral salpingo-oophorectomy (RRSO) results in an 80% reduction in risk of ovarian cancer and a 50% reduction in risk of breast cancer if the surgery is performed before the onset of menopause.
Legally Speaking: Tubal ligation failure results in wrongful pregnancy claim
Legally Speaking: Tubal ligation failure results in wrongful pregnancy claimSix months after a tubal ligation, a woman became pregnant. She gave birth by cesarean to a child who was diagnosed with sickle cell disease.
Use of ICSI on rise, but are outcomes better?
Use of ICSI on rise, but are outcomes better?Results of a retrospective cohort study show that use of intracytoplasmic sperm injection is on the rise but cast doubt on whether the technology is improving reproductive outcomes. Brian Levine, MD, MS provides commentary.
Interactive tools may help patients make informed decisions about prenatal testsA computerized decision-support guide may help women make more informed choices about prenatal testing, according to results of a randomized trial published in JAMA. The findings, which require validation in other populations, suggest that, were women better educated about the technology, fewer prenatal tests would be done.
Letters to the Editor: Readers respond to 'Whither the bimanual examination?'Writers emphatically agree with Dr. Lockwood's column on the ACP guideline regarding annual pelvic exams.
Prophylactic salpingectomy: The future of ovarian cancer prevention?Ovarian cancer is notorious for its late stage at diagnosis and its poor prognosis. In the absence of good screening tests, salpingectomy is the only form of prophylaxis for this cancer.
Do genetic factors explain recurrent pregnancy loss?
Do genetic factors explain recurrent pregnancy loss?There are 3 major patient populations affected by recurrent pregnancy loss. An editorial by Charles J. Lockwood, MD, MHCM.
Exclusive commentary on Supreme Court ruling on gene patentingOn June 13, the United States Supreme Court unanimously ruled that naturally occurring DNA cannot be subject to patent.