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Rh Disease Resource Center

Hemolytic disease in ABO-incompatible preterm infantsA study looks at the incidence of hemolytic reactions in preterm newborns.
Large study of maternal alloimmunization yields a surpriseRelative risk of stillbirth and preterm birth associated with less well-known antibodies was of similar magnitude to that found for anti-D.
John Queenan, Rh disease pioneerAn interview with the doctor behind the near-elimination of US deaths due to Rh disease.
Optimizing hemolytic disease management with third-trimester screeningDutch researchers reviewed data from 62,000 Rh-negative women to determine how to best detect and treat severe hemolytic disease of the fetus and newborn.
Vanishing twin syndrome affects NIPT resultsClinicians should be aware of the potential for confounding of NIPT results by cfDNA released from a vanishing twin.
Is routine anti-D prophylactic needed?Antenatal anti-D immunoglobulin helps reduce the incidence of RhD alloimmunization in Rh-negative women, but should it be administered to non-sensitized women prophylactically?
IV drug abuse linked to alloimmunizationA study found that IV drug abusing pregnant women had a two-fold higher relative risk of alloimmunization.
Targeted anti-RhD prophylaxis finds favor in CanadaResearch supports moving from routine antenatal anti-Rhesus D (RhD) prophylaxis in unsensitized RhD-negative pregnant women to a targeted approach.
SMFM Consult: The fetus at risk of anemia
SMFM Consult: The fetus at risk of anemiaA review of the causes, surveillance options, and management strategies for the pregnancy at risk of fetal anemia.
Kell sensitization can cause fetal anemia tooRh disease may get all the headlines, but immunologic reactions to the Kell antigen can be just as lethal to a K1-positive fetus—if not more so.